Although only a few months ago attention had been paid, the Zika virus appeared in Uganda in 1947. The disease is so ephemeral and its effects so slight and vague that many patients do not even know they are infected, and there is no reliable medical test which indicates that they have suffered. With that low profile, 70 years have passed until the Zika has become the center of a global health emergency. What has changed? What can we do? The real epidemic highlights the enormous differences in the infrastructures of countries to deal with infectious diseases.